CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
Poxvirus vectors represent versatile modalities for engineering novel vaccines and cancer immunotherapies.In addition to their oncolytic capacity and immunogenic influence, they can be Front Closure Bras readily engineered to express multiple large transgenes.However, the integration of multiple payloads into poxvirus genomes by traditional recombi